Mpox

Transmission in NYS is low following the 2022 outbreak. JYNNEOS vaccine remains available for high-risk individuals.

What is it?

Mpox (formerly called monkeypox) is caused by the mpox virus. Following a global outbreak in 2022 that peaked in New York City, mpox transmission in NYS has declined significantly. The 2022 outbreak was predominantly among gay, bisexual, and other men who have sex with men (GBMSM). The JYNNEOS vaccine remains available for high-risk individuals.

How it spreads

Spreads primarily through prolonged skin-to-skin contact with mpox rash lesions, scabs, or body fluids, including during sexual contact. Can also spread through contact with contaminated materials like bedding or clothing. Not primarily airborne, but can spread through respiratory secretions during prolonged close face-to-face contact.

Symptoms

Rash that may look like pimples, blisters, or sores — often starting on the genitals, anus, or face — along with fever, swollen lymph nodes, muscle aches, and fatigue. Rash lesions can be painful, especially in the genital/anal area. Illness typically lasts 2–4 weeks.

Who is at risk?

Gay, bisexual, and other men who have sex with men, and transgender individuals with multiple sexual partners face the highest current risk. Anyone with direct contact with mpox rash lesions or contaminated materials can be infected.

What you can do

Vaccine information

JYNNEOS vaccine (two doses, 4 weeks apart) is recommended for people at elevated risk of mpox, including GBMSM with multiple partners. Available through NYSDOH and local health departments.

Based on NYSDOH annual communicable disease report. Threat level reflects 2024 case counts compared to the 5-year baseline.